What is the structure of paramyxovirus?

What is the structure of paramyxovirus?

Structure. All paramyxoviruses are enveloped particles 150 to 300 nm in diameter. The tubelike, helically symmetrical nucleocapsid contains a monopartite, single-stranded, negative-sense RNA genome and an RNA-directed RNA polymerase.

What causes Paramyxoviridae?

The Paramyxoviridae are important agents of disease, causing age-old diseases of humans and animals (measles, rinderpest, canine distemper, mumps, respiratory syncytial virus (RSV), the parainfluenza viruses), and newly recognized emerging diseases (Nipah, Hendra, morbilliviruses of aquatic mammals).

What is Paramyxoviridae virus?

Paramyxoviridae (from Greek para- “by the side of” and myxa “mucus”) is a family of negative-strand RNA viruses in the order Mononegavirales. Vertebrates serve as natural hosts. Diseases associated with this family include measles, mumps, and respiratory tract infections.

What does paramyxovirus look like?

Paramyxoviruses encode negative-sense, single-stranded, monopartite RNA. They are enveloped and contain a helical nucleocapsid. They appear pleomorphic or spherical in electron micrographs.

Is RSV a paramyxovirus?

Introduction. Human respiratory syncytial virus (RSV) and human metapneumovirus (MPV) are members of the family Paramyxoviridae of the Mononegavirales order, comprising the nonsegmented negative-strand RNA viruses.

How is mumps passed?

The mumps virus replicates in the upper respiratory tract and is transmitted person to person through direct contact with saliva or respiratory droplets of a person infected with mumps. The risk of spreading the virus increases the longer and the closer the contact a person has with someone who has mumps.

What are the properties of paramyxovirus?

Paramyxoviridae consist of a lipid bilayer envelope, a nucleocapsid, and a matrix protein. Virions are typically spherical in shape but can also be pleiomorphic or filamentous with a diameter measuring approximately 150-200 nm. The envelope has surface projections or glycoprotein spikes that are 8-12 nm in length.