Does CABG require anticoagulation?
There is weak evidence for post-CABG anticoagulation, with warfarin and rivaroxaban providing no protection against graft failure but decreasing long-term major adverse cardiac events. Anticoagulation seems to be indicated only in post-CABG patients at high risk of future ischemic events.
Why would a patient need a CABG?
Your doctor uses coronary artery bypass graft surgery (CABG) to treat a blockage or narrowing of one or more of the coronary arteries to restore the blood supply to your heart muscle. Symptoms of coronary artery disease may include: Chest pain. Fatigue (severe tiredness)
What are the side effects of zalcitabine in adults?
Symptoms of peripheral neuropathy are tingling, numbness and pain in the feet or hands. Other side effects are headache, fever, abdominal pain, nausea, vomiting, diarrhea, rash, mouth ulcers, painful swallowing, and difficulty sleeping. What is the dosage for zalcitabine? The recommended dose for adults is 0.75 mg every 8 hours. What is HIV?
How is zalcitabine used in the treatment of cancer?
Zalcitabine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zalcitabine preferentially inhibits the gamma form of DNA polymerase present in tumor cell mitochondria, resulting in the inhibition of tumor cell mitochondrial DNA replication and tumor cell death. (NCI04)
Is there a generic version of zalcitabine?
Zalcitabine (Hivid – discontinued) is a medication used to treat HIV infection. Hivid is no longer available in the U.S. and there is no generic version. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this medication.
When to adjust the dose of Hivid zalcitabine?
Dose Adjustment for HIVID (zalcitabine) :For toxicities that are likely to be associated with HIVID (zalcitabine) (eg, peripheral neuropathy, severe oral ulcers, pancreatitis, elevated liver function tests especially in patients with chronic Hepatitis B), HIVID (zalcitabine) should be interrupted or dose reduced.
