What is Adluminal compartment?
In the adluminal compartment, spermatocytes derived from spermatogonia in the basal compartment undergo meiosis to form spermatids that progressively mature (spermiogenesis), with the more mature germ cells occupying positions closer to the lumen, until mature spermatozoa are released into the lumen of the tubule ( …
Where do Sertoli cells come from?
Sertoli cells are the epithelial supporting cells of the seminiferous tubules. They are derived from the epithelial sex cords of the developing gonads. They are tall simple columnar cells, which span from the basement membrane to the lumen.
What are the different Spermatogenetic cells?
The seminiferous epithelium that lines the tubules consists of three cell types: spermatogonia, which are stem cells; spermatocytes which are in the process of becoming sperm; and Sertoli cells, which nurture developing sperm and secrete a variety of products into the blood and the lumina of seminiferous tubules.
How do you identify Sertoli cells?
Sertoli cells have a characteristic oval nucleus with a dark nucleolus. The cytoplasmic contents and blood-testis barrier are better visualized under the electron microscope. Be sure not confuse the spermatogenic cells of the germinal epithelium with the Sertoli cells!
What does the adluminal compartment of the seminiferous tubule contain?
The adluminal compartment contains developing spermatocytes, spermatids, and mature spermatozoa that are released into the lumen of the seminiferous tubule. (From Matsumoto AM. The testis. In: Felig P, Frohman LA, eds. Endocrinology and Metabolism, 4th ed. New York, NY: McGraw-Hill; 2001:635-705.)
How are Sertoli cells used in the seminiferous tubules?
Sertoli Cell Diagram The stratified epithelium which lines the seminiferous tubules consists of spermatogenic cells interspersed between Sertoli cells. The Sertoli cells create a diffusion barrier which prevents the free passage of molecules from the blood capillaries of the interstitial tissue (1) into the seminiferous tubules.
Where are spermatogonia located in the seminiferous tubule?
The mammalian male germline stem cells (A s spermatogonia) lie at the periphery of the seminiferous tubules adjacent to the basement membrane (asterisk), and differentiation proceeds through multiple stages, creating spermatogonia, spermatocytes, spermatids, and spermatozoa, which are released into the lumen of the tubule.
Where do large molecules cannot pass between the basal and adluminal compartment?
Large molecules cannot pass between the basal and adluminal compartment – this is called the blood-testis barrier. This is a schematic diagram of part of a seminiferous tubule, showing the stages in the formation of spermatozoa. Like all epithelial cells, the Sertoli cells are avascular.
