What is odontoblast cell?
In vertebrates, an odontoblast is a cell of neural crest origin that is part of the outer surface of the dental pulp, and whose biological function is dentinogenesis, which is the formation of dentin, the substance beneath the tooth enamel on the crown and the cementum on the root.
What are the cells called that eventually change into ameloblasts?
2. The enamel organ. Amelogenesis involves the formation of a number of epithelium-derived cell types. The innermost layer, the inner enamel epithelium, is a single layer of cells that differentiate into ameloblasts.
What is the function of Odontoblast process?
The odontoblast process causes the secretion of hydroxyapatite crystals and mineralization of the matrix secreted by the odontoblasts.
Do odontoblasts secrete enamel?
While the odontoblast’s purpose is to secrete dentin, ameloblasts are only present during tooth development and function to deposit tooth enamel, forming the tooth’s hard outer layer.
How are ameloblast and odontoblast cells related?
Ameloblasts and Odontoblasts are both cells that are related to the formation of teeth. Ameloblasts work only during the development of teeth and form the deposit the outermost layer of the tooth which is the tooth enamel (the hard outer surface) and form the surface of the crown.
Where does the differentiation of ameloblasts take place?
Amelogenesis is the formation of enamel by ameloblasts of epithelial origin facing the odontoblast layer (Figure 26.3 ). Differentiation of ameloblasts is initiated by more advanced odontoblasts and the cells of stratum intermedium via molecular signals, such as BMP and FGF.
How does the ameloblast control the production of enamel?
Ameloblasts control ionic and organic compositions of enamel. It is theorized that a circadian clock (24-hour) probably regulates enamel production on a daily cycle by the ameloblasts (similar to osteoblasts in production of bone tissue).
When does apoptosis occur in the ameloblast?
The cells are part of the reduced enamel epithelium after enamel maturation and then subsequently undergo apoptosis before or after tooth eruption. These stages occur during the third and final stage of amelogenesis, called the maturation phase.
