How expensive is Krystexxa?
The cost for Krystexxa intravenous solution (8 mg/mL) is around $25,950 for a supply of 1 milliliter(s), depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Is Krystexxa FDA approved?
FDA-approved indication Krystexxa® (pegloticase) is indicated for the treatment of chronic gout in adult patients refractory to conventional therapy.
Who manufactures Krystexxa?
Savient Pharmaceuticals provided an update on its business activities related to the U.S. launch and commercialization of Krystexxa, a PEGylated uric acid specific enzyme for the treatment of chronic gout.
How long has Krystexxa been on the market?
The results from these trials resulted in the FDA approval of pegloticase (Krystexxa) in 2010. A 30-month open-label extension (OLE) study enrolling 96% of RCT completers assessed ongoing pegloticase efficacy in patients with tophaceous gout.
Where is KRYSTEXXA manufactured?
Manufacture of the product The Krystexxa finished product is manufactured at Sigma-Tau PharmaSource, Inc. Indianapolis, Indiana (STPS).
How do you infuse KRYSTEXXA?
KRYSTEXXA should be infused slowly over no less than 120 minutes. In the event of an infusion reaction, the infusion should be slowed, or stopped and restarted at a slower rate.
Is KRYSTEXXA a biologic?
CHOOSE THE BEST GOUT IV TREATMENT SETTING FOR YOU KRYSTEXXA is a biologic treatment, which means it’s made from a living source. Biologics are at the forefront of medical advances and can treat the causes of diseases rather than the symptoms.
How often is KRYSTEXXA given?
Unlike medicines you take long term, KRYSTEXXA is given every 2 weeks for about 6 months.
When was KRYSTEXXA FDA approved?
September 15, 2010 — The US Food and Drug Administration (FDA) has approved pegloticase (Krystexxa; Savient Pharmaceuticals, Inc) as the first and only treatment for chronic gout in adults refractory to conventional therapy.
What drug class is KRYSTEXXA?
Krystexxa Overview Krystexxa belongs to a group of drugs called PEGylated uric acid specific enzymes. It works by decreasing the amount of uric acid in the body.
Is Rasburicase the same as pegloticase?
In contrast to rasburicase, pegloticase is pegylated to increase its elimination half-life from about eight hours to ten or twelve days, and to decrease the immunogenicity of the foreign uricase protein.
Are there any side effects to taking Krystexxa?
The most common side effects in patients taking KRYSTEXXA were gout flare-ups or attacks, allergic reactions, nausea, bruising, sore throat, constipation, chest pain, and vomiting. This is not a complete list of all possible side effects. Tell your doctor or treatment team if you have any side effect that bothers you or that does not go away.
How is Krystexxa used to treat gout in adults?
KRYSTEXXA is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments. What is the most important information I should know about KRYSTEXXA (pegloticase)? Serious allergic reactions may happen in some patients who receive KRYSTEXXA.
Can you take Krystexxa if you have G6PD deficiency?
“Before you start KRYSTEXXA, we’ll test you for a rare blood disorder called G6PD deficiency, or favism, that would prevent you from taking KRYSTEXXA.” “ How long does KRYSTEXXA take to work?”
