Which is leukocyte common antigen?
CD45 antigen (leukocyte common antigen), a unique and ubiquitous membrane glycoprotein with a molecular mass of about 200 kDa, is expressed on almost all hematopoietic cells except for mature erythrocytes. However, the biological function of this glycoprotein still remains to be resolved.
What is LCA immunohistochemistry?
For In Vitro Diagnostic Use Leukocyte Common Antigen (LCA) Cocktail [PD7/26+2B11] is a mouse monoclonal antibody cocktail that is intended for laboratory use in the qualitative identification of leukocyte cellular surface marker protein CD45 by immunohistochemistry (IHC) in formalin-fixed paraffin- embedded (FFPE) …
What is the function of CD45?
Function. The protein product of this gene, best known as CD45, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
What is LCA in lymphoma?
Immunohistochemical localization of human leukocyte common antigen (LCA), a major membrane glycoprotein restricted to leukocytes, was evaluated in paraffin sections of a wide variety of hematopoietic and nonhematopoietic tissues (294 specimens) with monoclonal antibodies (PD7/26 and 2B11).
What is leukocyte produces antibodies?
Human leukocyte antigen. These particular antigens stimulate the multiplication of T-helper cells (also called CD4 positive T cells), which in turn stimulate antibody -producing B-cells to produce antibodies to that specific antigen. Self-antigens are suppressed by regulatory T cells .
What is role in leukocyte in the immune response?
Lymphocyte, type of white blood cell (leukocyte) that is of fundamental importance in the immune system because lymphocytes are the cells that determine the specificity of the immune response to infectious microorganisms and other foreign substances. In human adults lymphocytes make up roughly 20 to 40 percent of the total number of white blood cells.
What is positive HLA B27?
A positive test means HLA-B27 is present. It suggests a greater-than-average risk for developing or having certain autoimmune disorders. An autoimmune disorder is a condition that occurs when the immune system mistakenly attacks and destroys healthy body tissue.
What is the abbreviation for human leukocyte antigen?
HLA stands for human leukocyte antigen (also Human Leukocyte Antigens and 231 more)
