Which drugs cause glaucoma toxicity?
Timolol (generic name) is a frequently used medication for the control of glaucoma. Benzalkonium chloride (BAK) is a commonly used preservative in ophthalmic solutions with a broad range of antimicrobial activity; however, this nonspecificity can result in toxicity.
Are preservatives in eye drops harmful?
In fact any chemical added to eye drops, such as the preservative and buffering agents just mentioned, have the potential to harm the eye. Toxicity from pharmaceutical agents can result in decreased visual acuity and/or patient comfort that can lead to decreased compliance.
Is Benzalkonium Chloride safe for humans?
This cosmetic ingredient is not a sensitizer to normal humans at concentrations of 0.1%, but may be to individuals with diseased skin. It is concluded that Benzalkonium Chloride can be safely used as an antimicrobial agent at concentrations up to 0.1%.
Is benzalkonium chloride safe for skin?
The safety of Benzalkonium Chloride has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated scientific data and concluded that Benzalkonium Chloride, at concentrations up to 0.1% free, active ingredient, was safe as a cosmetic ingredient.
Is benzalkonium chloride dangerous?
About BENZALKONIUM CHLORIDE: Biocide , preservative and surfactant associated with severe skin, eye, and respiratory irritation and allergies, benzalkonium chloride is a sensitizer especially dangerous for people with asthma or skin conditions such as eczema.
What are the uses of benzalkonium chloride?
Uses of Benzalkonium Chloride: It is used to prevent skin infections. It is used to clean wounds.
Does benzalkonium chloride cause allergy?
Benzalkonium chloride (BAK) is a widely used quaternary ammonium cationic detergent. It has occasionally been reported as a cause of allergic dermatitis. The agent is the most commonly used preservative in ophthalmic medications, solutions for contact lenses, and “artificial tears.” A physician developed a severe allergic conjunctivitis from an ophthalmic solution containing BAK.
How does benzalkonium chloride work?
Benzalkonium Chloride is primarily used as a preservative and antimicrobial agent, and secondarily used as a surfactant . It works by killing microorganisms and inhibiting their future growth, and for this reason frequently appears as an ingredient in antibacterial hand wipes, antiseptic creams and anti-itch ointments.
