Is steatocystoma multiplex serious?
In steatocystoma multiplex, the tendency to develop cysts is inherited in an autosomal dominant fashion, so one parent can be expected to also have steatocystoma multiplex. It may also occur sporadically….
| Steatocystoma multiplex | |
|---|---|
| Other names | Epidermal polycystic disease and Sebocystomatosis |
| Specialty | Dermatology |
Is steatocystoma multiplex cancerous?
At present, there are few reports of lung cancer patients with skin lesions involving the chest, back, abdomen, and all four limbs, at the same time, as described here. Steatocystoma multiplex is an uncommon skin disorder characterized by the development of multiple asymptomatic, variably-sized cysts.
How do you get rid of steatocystoma multiplex?
Individual cysts can be removed surgically. In most cases, small incisions (cuts into the skin) allow the cyst and its contents to be extracted through the opening. If it is tethered to the underlying skin, excision biopsy may be necessary. Cysts can also be removed by laser, electrosurgery or cryotherapy.
Can Steatocystoma be cured?
Treatment options for steatocystoma multiplex are limited and have had varying degrees of success. The most effective treatment method is thought to be removal of cysts by surgery. However, cosmetic concerns, time, cost, and pain need to be considered because affected individuals often have multiple cysts.
What is inside a Steatocystoma?
Steatocystoma multiplex is a skin disorder characterized by the development of multiple noncancerous (benign) cysts known as steatocystomas. These growths begin in the skin’s sebaceous glands, which normally produce an oily substance called sebum that lubricates the skin and hair. Steatocystomas are filled with sebum.
How do I know if I have Steatocystoma?
If you encounter a patient with bumps, typically measuring one to two centimeters wide (though they can be larger in diameter), that formed under relatively normal-looking skin and appear predominantly on the person’s chest, upper arms, neck, face, and legs, it may be steatocystoma.
What kind of cyst is steatocystoma multiplex?
Steatocystoma multiplex is a skin disorder characterized by the development of multiple noncancerous (benign) cysts known as steatocystomas. These growths begin in the skin’s sebaceous glands, which normally produce an oily substance called sebum that lubricates the skin and hair.
What causes steatocystoma multiplex on the hands?
Steatocystoma multiplex can be caused by mutations in the KRT17 gene. This gene provides instructions for making a protein called keratin 17, which is produced in the nails, the hair follicles, and the skin on the palms of the hands and soles of the feet.
What happens to keratin 17 in steatocystoma multiplex?
Keratin 17 partners with a similar protein called keratin 6b to form networks that provide strength and resilience to the skin, nails, and other tissues. The KRT17 gene mutations that cause steatocystoma multiplex alter the structure of keratin 17, preventing it from forming strong, stable networks within cells.
Can a person with steatocystoma multiplex have palmoplanta congenita?
Pachyonychia congenita is also associated with more severe nail abnormalities and a painful skin condition called palmoplantar keratoderma, which are not usually found in people with steatocystoma multiplex. In some cases, people with steatocystoma multiplex do not have an identified mutation in the KRT17 gene.
