What is double filtration plasmapheresis?
Double Filtration Plasmapheresis (DFPP) is a blood purification process to get rid of pathogenic substances (viruses, auto-antibodies, immune complex, cholesterol, etc.) from our body by using specific filters for specific diseases.
Do you need central line for plasmapheresis?
Central lines, as opposed to peripheral lines, are required for membrane-based plasmapheresis because of their higher flow rates of roughly 100-150 mL/min, as compared with 50-70 mL/min for centrifuge-based equipment.
How many times can the patient treat with plasmapheresis?
According to federal regulations, a person can donate plasma up to twice a week. Donation sessions usually take about 90 minutes. If you’re receiving plasmapheresis as treatment, the procedure can last between one and three hours. You may need as many as five treatments per week.
How much plasma is removed in plasmapheresis?
Typically, a 300 ml batch of blood is removed at a time and centrifuged to separate plasma from blood cells. Continuous flow centrifugation: Two venous lines are used.
How does double filtration plasmapheresis ( DFPP ) work?
Double Filtration Plasmapheresis (DFPP) is a blood purification process to get rid of pathogenic substances (viruses, auto-antibodies, immune complex, cholesterol, etc.) from our body by using specific filters for specific diseases. The DFPP is really simple.
How are platelets and plasma separated in pheresis?
Pheresis, or apheresis, describes any process that removes the blood, filters and retains elements of it, then returns the blood to the body. Platelets, red blood cells, white blood cells, or plasma may be separated.
What are the different types of plasmapheresis filters?
AVpaed, AV400S, AV600S and AV1000S filters have different surface areas but the same reliable membrane. Substances with a molecular weight of up to approximately 30 kDa can be eliminated, while essential plasma proteins like albumin and cellular blood constituents are retained.
Why are Fresenius plasmapheresis filters safe to use?
An important safety aspect is the 100% leakage-testing of all filters, with just sterile water and sterile filtered air. This is only possible because of the special structure of the Fresenius Polysulfone membrane – and the absence of pore filling agents like glycerin.
