What is REGRANEX gel used for?
This medication is used to treat certain foot/leg ulcers in people with diabetes. It is used along with good foot/leg care (e.g., keeping pressure off the wound) to help the ulcer heal completely. Becaplermin works by attracting certain natural substances to the ulcer that help wound healing.
Is REGRANEX over the counter?
Regranex is a prescription medication used to treat diabetic foot ulcers in patients with normal blood flow in the feet and legs. It is usually used along with good foot care to help ulcers to heal completely. There is no generic alternative available.
How long does REGRANEX last?
REGRANEX should be applied once daily to the ulcer until complete healing has occurred. If the ulcer does not decrease in size by approximately 30% after 10 weeks of treatment or complete healing has not occurred in 20 weeks, continued treatment with REGRANEX should be reassessed.
Who manufactures REGRANEX?
REGRANEX (becaplermin) Gel, 0.01% | Smith & Nephew – US Professional.
How often should you apply Regranex 0.01% gel?
REGRANEX Gel 0.003% or 0.01% or placebo gel was applied once a day and covered with a saline moistened dressing. After approximately 12 hours, the gel was gently rinsed off and a saline moistened dressing was then applied for the remainder of the day.
Are there any side effects to taking Regranex gel?
In clinical trials, erythematous rashes occurred in 2% of subjects treated with Regranex gel (and good ulcer care) or placebo (and good ulcer care), and none in subjects receiving good ulcer care alone. Subjects treated with Regranex Gel did not develop neutralizing antibodies against becaplermin.
When to use Regranex gel for diabetic ulcers?
Regranex gel is indicated for the treatment of lower extremity diabetic neuropathic ulcers that extend into the subcutaneous tissue or beyond and have an adequate blood supply, when used as an adjunct to, and not a substitute for, good ulcer care practices including initial sharp debridement, pressure relief and infection control.
What kind of growth factor is Regranex gel?
REGRANEX Gel contains becaplermin, a recombinanthuman platelet-derived growth factor for topical administration. Becaplermin is produced by recombinant DNA technologyby insertion of the gene for the B chain of platelet-derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae.
