Is Eperisone safe for pregnancy?
Eperisone has not been established to be safe for use by pregnant women; therefore the drug should only be used in pregnant women, or women who may be pregnant, if the expected therapeutic benefits will outweigh the possible risks associated with treatment.
What is the use of Eperisone hydrochloride?
Eperisone hydrochloride (4′-ethyl-2-methyl-3-piperidinopropiophenone hydrochloride) is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain.
How long does Eperisone take to work?
Absorption: Time to peak plasma concentration: 1.6-1.9 hours.
How many days can I take Eperisone?
The total duration of treatment will be 14 days. Patients will be screened for baseline parameters and will then be randomized, as per the predetermined randomization schedule, into two groups. Patients will be treated with either Eperisone-HCl (Myonal) or placebo for a period of 14 days.
What are the side effects of eperisone in humans?
Description: Eperisone is centrally-acting agent which relaxes skeletal muscles by inhibition of experimentally-induced muscle rigidity, suppression of spinal reflexes and reduction of muscle spindle sensitivity via γ-motor neurons. It also dilates vascular smooth muscles and augments blood flow.
Where does Eperisone HCL have an analgesic action?
This suggests that eperisone HCl possesses an analgesic action at the spinal cord level.
How does Eperisone work in the spinal cord?
Eperisone. Analgesic Action and Inhibition of the Pain Reflex in the Spinal Cord: When eperisone HCl is perfused into the spinal cord of rats, a tail pinch-induced pain reflex is suppressed, but the reflex returns with the withdrawal of eperisone HCl. This suggests that eperisone HCl possesses an analgesic action at the spinal cord level.
How is eperisone hydrochloride used to treat AMSP?
Eperisone hydrochloride was effective and well tolerated for the treatment of patients with AMSP with LBP. Eperisone hydrochloride was effective and well tolerated for the treatment of patients with AMSP with LBP.
