What is cystitis glandularis?
Cystitis glandularis (CG) is an unusual proliferative disorder of the urinary bladder, which is characterized by transitional cells that have undergone glandular metaplasia (1).
Can cystitis glandularis be cured?
Usually, cystitis glandularis would be treated with surgery. The disease could be induced by chronic bladder inflammation, stones, obstruction, neurogenic bladder, the bladder exstrophy and other primary disease, but there is no satisfactory evidence about the link until now.
Is cystitis glandularis precancerous?
Cystitis glandularis (CG) has been hypothesized as a potential precursor of adenocarcinoma, although this remains controversial. The present study reports data accumulated from 166 cases of cystitis glandularis with follow-up periods ranging between 0.5 and 17 years.
What is pathophysiology of cystitis?
The pathogenesis of complicated cystitis include obstruction and stasis of urine flow. Complicated cystitis is usually a result of an abnormality in the structure or function of the urinary tract. This abnormality can result from various causes like foreign bodies such as: kidney stones.
How are cystitis cystica and glandularis defined?
When florid they may simulate neoplasm (see Florid von Brunn Nests) Cystitis cystica and cystitis glandularis are defined as lumens formed within von Brunn nests. They frequently are intermixed and may form a spectrum. Spaces may be encompassed by size of usual nests or be cystically dilated.
How is cystitis glandularis treated in women?
This rare pathology is managed by endoscopic bladder resection, with repeated cystoscopy as a monitoring tool. Extensive surgical is needed in severe or recurrent cases. We present here-in a case of a female patient having cystitis glandularis presenting with lower urinary tract symptoms. We review equally data reported in literature.
Is it normal to have cystitis cystica?
They are considered normal. Cystitis cystica is a similar lesion to cystitis glandularis, where the central area of the Von Brunn’s nests have degenerated, leaving cystic lesions. Other metaplastic entities in the urinary bladder include squamous metaplasia and nephrogenic adenoma.
How are goblet cells different from cystitis glandularis?
In the case of cystitis glandularis, the buds then differentiate into mucin-producing goblet cells (whereas in cystitis cystica they differentiate into fluid-filled cysts). In most cases, examples of both conditions can be identified histologically.
