What causes antibiotic-associated hemorrhagic colitis?

What causes antibiotic-associated hemorrhagic colitis?

Colitis is a well-known complication of treatment with antibiotic agents. The disease is generally thought to be caused by overgrowth of toxin-producing Clostridium difficile in the colon. Antibiotic-associated hemorrhagic colitis is a distinct form of antibiotic-associated colitis in which C. difficile is absent.

Where is Klebsiella oxytoca from?

Klebsiella oxytoca (KO) is one of several Klebsiella bacteria. These bacteria are naturally found in the intestinal tract, mouth, and nose. They’re considered healthy gut bacteria inside your intestines. Outside the gut, however, these bacteria can cause serious infections.

Does Klebsiella oxytoca cause diarrhea?

Klebsiella oxytoca is a known cause of antibiotic-associated diarrhea1–4 and hemorrhagic colitis.

What is Aahc in microbiology?

Abstract. Klebsiella oxytoca was recently described as the causative organism for antibiotic-associated hemorrhagic colitis (AAHC).

What kind of colitis is caused by Klebsiella oxytoca?

Klebsiella oxytoca responsible for antibiotic-associated hemorrhagic colitis. The antibiotic-associated hemorrhagic colitis is a serious bowel inflammation, which usually occurs under a penicillin therapy and is not caused by Clostridium difficile.

Can a healthy person get a Klebsiella infection?

To get a Klebsiella infection, a person must be exposed to the bacteria. For example, Klebsiella must enter the respiratory (breathing) tract to cause pneumonia, or the blood to cause a bloodstream infection. Most healthy people do not get Klebsiella infections.

Which is the most important Klebsiella species?

Of the pathogenic Klebsiella species, K. pneumoniae is the most prevalent and clinically important. Infections with K. pneumoniae are usually hospital-acquired and occur primarily in patients with impaired host defenses.

Can a liver abscess be caused by Klebsiella pneumoniae?

(See “Invasive liver abscess syndrome caused by Klebsiella pneumoniae” .) The epidemiology, clinical features, diagnosis, and treatment of infections due to K. pneumoniae will be reviewed here. The microbiology and pathogenesis of K. pneumoniae infection are discussed separately.

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