When do you add anaerobic coverage?
Anaerobic coverage may be indicated in various infections including but not limited to intra-abdominal infections, aspiration pneumonia, diabetic foot infections/osteomyelitis, and gynecologic infections. Gram-positive oral anaerobes are covered by most beta-lactams including penicillin.
Which antibiotics have anaerobic coverage?
The most effective antimicrobials against anaerobic organisms are metronidazole, the carbapenems (imipenem, meropenem and ertapenem), chloramphenicol, the combinations of a penicillin and a beta-lactamase inhibitor (ampicillin or ticarcillin plus clavulanate, amoxicillin plus sulbactam, and piperacillin plus tazobactam …
Does metronidazole eliminate Aerobes or anaerobes?
METRONIDAZOLE IN CLINICAL PRACTICE For treatment of mixed aerobic and anaerobic infection, metronidazole should be used in combination with other antibacterial agents that are appro- priate for the treatment of the aerobic infection, because it is ineffective against aerobic bacteria (Table 1).
Does Piptaz cover anaerobic?
Piperacillin/tazobactam is a beta-lactam/beta-lactamase inhibitor combination with a broad spectrum of antibacterial activity encompassing most Gram-positive and Gram-negative aerobic bacteria and anaerobic bacteria, including many pathogens producing beta-lactamases.
Why is piperacillin tazobactam used together?
Piperacillin and tazobactam is a combination penicillin antibiotic that is used to treat many different infections caused by bacteria, such as stomach infections, skin infections, pneumonia, and severe uterine infections. This medicine is sometimes given together with other antibiotics.
What is not covered by meropenem?
Meropenem is active against methicillin-susceptible S. aureus and most strains of methicillin-susceptible coagulase-negative staphylococci. However, as with other carbapenems, meropenem has poor activity against MRSA and methicillin-resistant coagulase-negative staphylococci.
Does Zosyn cover anaerobes?
Vanc/Zosyn is not elegant, but will cover most infections: Gram positives including MRSA , Gram negatives including most Pseudomonas , and anaerobes. Excellent range of site penetration including lungs, abdomen, urine, and skin/soft tissues.
Does ceftriaxone cover anaerobes?
If Cefuroxime , Ceftriaxone or Cefotaxime were used then Metronidazole would need to be added to cover the anaerobes. You would not use Cefuroxime, Ceftriaxone or Cefotaxime with Clindamycin as this poses too high a risk for Clostridium difficile associated diarrhoea (CDAD).
What does antibiotic cover anaerobic bacteria?
Piperacillin and tazobactam are given together as injectable antibiotics for anaerobic bacterial infection. The brand name of the drug combination is Zosyn Piperacillin-Tazobactam Piperacillin/tazobactam is used to treat a wide variety of bacterial infections. , and it contains the antibiotic piperacillin sodium and the β-lactamase inhibitor tazobactam sodium. Some of the side effects of the drug include skin rash, nausea, and vomiting.
