What causes right ventricular outflow tract obstruction?
Right ventricular outflow tract obstruction may be caused by defects of the pulmonary valve, adjacent parts of the right ventricle, and main pulmonary artery that cause obstruction of the outflow of blood from the right ventricle.
How is Lvot obstruction treated?
Pharmacological control of left ventricular outflow tract obstruction. The pharmacological treatment of LVOT obstruction and related symptoms in HCM patients is based on a time-honoured combination of negative inotropic agents, including β-blockers, calcium antagonists, and disopyramide.
What is right ventricular outflow tract obstruction?
Right ventricular outflow obstruction in the area of the pulmonary valve causes hypertrophy of the right ventricle and a higher pressure in the right ventricle. Thus, deoxygenated blood flows through the hole in the heart from the right to the left ventricle.
What is outflow tract obstruction?
Left ventricular outflow tract obstruction (LVOTO) is a recognised feature of hypertrophic cardiomyopathy. It is caused by the thickened heart muscle and the abnormal movement of the mitral valve. This is the main mechanism of debilitating symptoms in hypertrophic cardiomyopathy patients.
What is severe Lvot obstruction?
LVOT obstruction is defined as a peak instantaneous gradient greater than or equal to 30 mm Hg. A gradient greater than or equal to 50 mm Hg is generally recognized as the threshold at which LVOT obstruction becomes hemodynamically significant.
Is Rvot genetic?
ARVD is a genetic disorder of myocardium in which there is fatty infiltration of the right ventricular free wall, and accounts for up to 10% of sudden cardiac death in individuals under 65 years of age. Affected individuals often present with exercise-induced episodes of VT accompanied by LBBB morphology.
