What is piperacillin sodium used for?
Piperacillin and tazobactam injection is used to treat pneumonia and skin, gynecological, and abdominal (stomach area) infections caused by bacteria. Piperacillin is in a class of medications called penicillin antibiotics. It works by killing bacteria that cause infection.
Is piperacillin a strong antibiotic?
When used alone, piperacillin lacks strong activity against the Gram-positive pathogens such as Staphylococcus aureus, as the beta-lactam ring is hydrolyzed by the bacteria’s beta-lactamase….Piperacillin.
| Clinical data | |
|---|---|
| show IUPAC name | |
| CAS Number | 61477-96-1 |
| PubChem CID | 43672 |
| IUPHAR/BPS | 422 |
How do you give piperacillin?
Piperacillin/Tazobactam 2 g / 0.25 g is administered by intravenous infusion (over 30 minutes). Piperacillin/Tazobactam 4 g / 0.5 g is administered by intravenous infusion (over 30 minutes). For reconstitution instructions, see section 6.6.
What are the side effects of piperacillin?
Rare
- Agitation.
- bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site.
- bone pain.
- bruising.
What is the chemical structure of piperacillin sodium?
The chemical structure of piperacillin sodium is: Tazobactam sodium, a derivative of the penicillin nucleus, is a penicillanic acid sulfone. Its chemical name is sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1 azabicyclo[3.2.0]heptane-2-carboxylate-4,4-dioxide.
Which is the best diluent for piperacillin sodium?
Diluents that are compatible with piperacillin sodium and tazobactam sodium include 0.9% sodium chloride injection, sterile water for injection (maximum recommended volume is 50 mL), 5% dextrose injection, and 6% dextran in 0.9% sodium chloride injection.
How long is an infusion of piperacillin sodium?
Piperacillin sodium and tazobactam sodium is administered by IV infusion over 30 minutes.
How much sodium is in tazobactam and piperacillin?
Piperacillin and tazobactam for injection contains 54 mg (2.35 mEq) of sodium per gram of piperacillin in the combination product. At the usual recommended doses, patients would receive between 648 and 864 mg/day (28.2 and 37.6 mEq) of sodium.
