Is DNA polymerase 2 found in eukaryotes?
DNA Polymerase II, Bacterial Members of the family B polymerases are found throughout the Archaea; and, interestingly, the three replicative DNA polymerases of eukaryotic cells, as well as additional repair DNA polymerases, belong to family B.
What does DNA polymerase 2 do in eukaryotes?
Eukaryotic RNA polymerase II (pol II) is a 12-subunit DNA-dependent RNA polymerase that is responsible for transcribing nuclear genes encoding messenger RNAs and several small nuclear RNAs (1).
How do eukaryotic RNA polymerases I II and III differ from each other how are they similar?
coli RNA polymerase. RNA polymerases I and III contain the same two non-identical α-like subunits, whereas polymerase II has two copies of a different α-like subunit. All three polymerases share four other common subunits. In addition, each RNA polymerase contains three to seven unique smaller subunits.
Which of the following RNA is transcribed by RNA polymerase 2 in eukaryotes?
Eukaryotic cells contain three distinct nuclear RNA polymerases that transcribe different classes of genes (Table 6.1). Protein-coding genes are transcribed by RNA polymerase II to yield mRNAs; ribosomal RNAs (rRNAs) and transfer RNAs (tRNAs) are transcribed by RNA polymerases I and III.
Where are the RNA polymerase II core promoters located?
RNA polymerase II (Pol II) core promoters are specialized DNA sequences at transcription start sites of protein-coding and non-coding genes that support the assembly of the transcription machinery and transcription initiation.
What is the function of DNA polymerase II?
DNA Polymerase II is coded by polB gene. It is made up of 7 subunits. Its main role is in repair and also a backup of DNA polymerase III. It has 3’→5’ exonuclease activity. DNA Polymerase III is the main enzyme for replication in E.coli. It is coded by polC gene. The polymerization and processivity rate is maximum in DNA polymerase III.
How does RNA polymerase II transcribe genes in the eukaryotic cell?
RNA polymerase II (RNAPII) transcribes the major share of eukaryotic genes. During elongation, the transcription machinery needs to move histones out of the way every time it encounters a nucleosome.
How many subunits are in RNA polymerase II?
RNA polymerases I, II, and III are large and complex proteins, consisting of 14, 12, and 17 subunits, respectively. Five of these subunits are shared, and a further two are found in RNA polymerases I and III, but not in RNA polymerase II.
