What is emodin used for?
Emodin is used in combination with paclitaxel against breast cancer and ovarian cancer where it acts as a tyrosine kinase inhibitor and suppress growth and transformation of cancer cells (Vinod et al., 2013a, b). Emodin is also a powerful anti-oxidant which is reported to modulate ROS pathways (Yi et al., 2004).
Is emodin safe?
Conclusions. In summary, our studies establish that 1) emodin is safe for use in both male and female mice when given at 20, 40, and 80 mg/kg doses for 12 weeks and 2) sex differences should be considered when establishing dosing intervals for emodin treatment.
What is the source of emodin?
Emodin is an anthraquinone obtained from traditional herb Rhubarb or Rheum officinale and Polygonum cuspidatum. This has been evaluated for its immunosuppressive and antiinflammatory activities.
What are the medicinal uses of anthraquinone glycosides?
Many of them possess antibacterial, antiparasitic, insecticidal, fungicidal, and antiviral properties. They are also used as anticancer agents. Anthraquinones are active components of many plant blends which are used as medicines and exhibit laxative, diuretic, estrogenic, and immunomodulatory effects.
Are there any real medical uses for emodin?
Data from animal and experimental studies demonstrate strong anti-inflammatory and antioxidant effects that may prove useful in cancer, osteoporosis, and cardiovascular, CNS, liver, metabolic, and respiratory conditions. Antimicrobial and laxative activity has also been noted. No clinical data exist to support any of these uses.
How old does a child have to be to take Imodium?
IMODIUM® Anti-Diarrheal Oral Solution (liquid) Diarrhea Medicine For Children Ages 6 and Up. If your child has diarrhea, take comfort knowing that IMODIUM A-D Oral Solution (liquid) for use with children is the only OTC brand anti-diarrheal that’s FDA-approved for children aged 6-11.
Can a 2 year old take an acetaminophen tablet?
Children’s acetaminophen can be taken as liquid or chewable tablet. If your child is under age 2 years, check with your health care provider before giving your child acetaminophen. To give the correct dose, you will need to know your child’s weight.
How is emodin used in pregnancy and lactation?
Pregnancy/Lactation. Anthranoid metabolites may be excreted in breast milk. Emodin has been shown to impair embryonic development in mouse blastocysts, and in vitro studies have demonstrated a dose-dependent inhibitory effect on sperm motility but not sperm viability.
